Defective factor VIII causes hemophilia A
REACTOME PATHWAYThe Defective factor VIII causes hemophilia A pathway (Reactome ID: R-HSA-9662001) involves 1 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Defective factor VIII causes hemophilia A
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Rivaroxaban | — | 999 |
| 2 | apixaban [Supplementary Concept] | — | 997 |
| 3 | Gabexate | — | 300 |
About the Defective factor VIII causes hemophilia A Pathway
The Defective factor VIII causes hemophilia A pathway is catalogued in Reactome (ID: R-HSA-9662001) and involves 1 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include F10.