What compounds affect the Translation of Structural Proteins pathway?

29 compounds in the BiohacksAI corpus have documented interactions with genes in the Translation of Structural Proteins pathway (Reactome ID: R-HSA-9683701). These compounds target 5 genes within this pathway.

What genes are in the Translation of Structural Proteins pathway?

The Translation of Structural Proteins pathway involves 5 genes. Key genes include: GALNT1, GANAB, GSK3A, GSK3B, SUMO1.

Translation of Structural Proteins

REACTOME PATHWAY

Reactome: R-HSA-96837015 genes29 compounds

The Translation of Structural Proteins pathway (Reactome ID: R-HSA-9683701) involves 5 genes and is affected by 29 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

GALNT1 GANAB GSK3A GSK3B SUMO1

Compounds Affecting Translation of Structural Proteins

#	Compound	Targets Hit	Studies
1	alsterpaullone	—	12
2	kenpaullone	—	8
3	indirubin	—	300
4	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
5	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
6	Kaempferols	—	300
7	Quercetin	—	300
8	chrysin	—	300
9	fisetin	—	78
10	sp600125	—	117
11	Zearalenone (S-(E))-3,4,5,6,8,10-Hexahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradec in-1,7(8H)-dione.	—	300
12	Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is	—	300
13	Lithium Chloride	—	300
14	ly294002	—	11
15	Sorafenib	—	300
16	egcg	—	300
17	Rutin	—	300
18	Ursolic Acid	—	300
19	Oleanolic Acid	—	300
20	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
21	Tannins Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS).	—	300
22	Chlorhexidine	—	299
23	piceatannol	—	300
24	Cefdinir	—	298
25	Cefixime	—	300
26	Hexachlorophene	—	300
27	Oxytetracycline	—	300
28	1-Deoxynojirimycin	—	299
29	urolithin d	—	2

About the Translation of Structural Proteins Pathway

The Translation of Structural Proteins pathway is catalogued in Reactome (ID: R-HSA-9683701) and involves 5 genes. In the BiohacksAI corpus, 29 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include GALNT1, GANAB, GSK3A, GSK3B, SUMO1.