ASP-3026-resistant ALK mutants
REACTOME PATHWAYThe ASP-3026-resistant ALK mutants pathway (Reactome ID: R-HSA-9717264) involves 1 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting ASP-3026-resistant ALK mutants
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Crizotinib | — | 298 |
| 2 | Quercetin | — | 300 |
| 3 | cycloheximide | — | 300 |
About the ASP-3026-resistant ALK mutants Pathway
The ASP-3026-resistant ALK mutants pathway is catalogued in Reactome (ID: R-HSA-9717264) and involves 1 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ALK.