Nucleotide salvage defects
REACTOME PATHWAYThe Nucleotide salvage defects pathway (Reactome ID: R-HSA-9734207) involves 2 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Nucleotide salvage defects
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Pentostatin | — | 297 |
| 2 | Coformycin | — | 171 |
| 3 | Adenosine | — | 298 |
| 4 | guanine | — | 299 |
| 5 | Guanosine Monophosphate | — | 300 |
| 6 | Inosine Monophosphate Inosine 5'-Monophosphate. | — | 299 |
About the Nucleotide salvage defects Pathway
The Nucleotide salvage defects pathway is catalogued in Reactome (ID: R-HSA-9734207) and involves 2 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ADA, HPRT1.