Defective HPRT1 disrupts guanine and hypoxanthine salvage
REACTOME PATHWAYThe Defective HPRT1 disrupts guanine and hypoxanthine salvage pathway (Reactome ID: R-HSA-9734281) involves 1 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Defective HPRT1 disrupts guanine and hypoxanthine salvage
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | guanine | — | 299 |
| 2 | Guanosine Monophosphate | — | 300 |
| 3 | Inosine Monophosphate Inosine 5'-Monophosphate. | — | 299 |
About the Defective HPRT1 disrupts guanine and hypoxanthine salvage Pathway
The Defective HPRT1 disrupts guanine and hypoxanthine salvage pathway is catalogued in Reactome (ID: R-HSA-9734281) and involves 1 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include HPRT1.