Defective ADA disrupts (deoxy)adenosine deamination
REACTOME PATHWAYThe Defective ADA disrupts (deoxy)adenosine deamination pathway (Reactome ID: R-HSA-9734735) involves 1 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Defective ADA disrupts (deoxy)adenosine deamination
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Pentostatin | — | 297 |
| 2 | Coformycin | — | 171 |
| 3 | Adenosine | — | 298 |
About the Defective ADA disrupts (deoxy)adenosine deamination Pathway
The Defective ADA disrupts (deoxy)adenosine deamination pathway is catalogued in Reactome (ID: R-HSA-9734735) and involves 1 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ADA.