Diseases of nucleotide metabolism
REACTOME PATHWAYThe Diseases of nucleotide metabolism pathway (Reactome ID: R-HSA-9735804) involves 3 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Diseases of nucleotide metabolism
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | guanine | — | 299 |
| 2 | Pentostatin | — | 297 |
| 3 | Coformycin | — | 171 |
| 4 | Adenosine | — | 298 |
| 5 | Guanosine Monophosphate | — | 300 |
| 6 | Inosine Monophosphate Inosine 5'-Monophosphate. | — | 299 |
About the Diseases of nucleotide metabolism Pathway
The Diseases of nucleotide metabolism pathway is catalogued in Reactome (ID: R-HSA-9735804) and involves 3 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ADA, HPRT1, PNP.