TGFBR3 regulates TGF-beta signaling
REACTOME PATHWAYThe TGFBR3 regulates TGF-beta signaling pathway (Reactome ID: R-HSA-9839389) involves 3 genes and is affected by 8 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting TGFBR3 regulates TGF-beta signaling
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Dasatinib | — | 299 |
| 2 | Hesperidin | — | 300 |
| 3 | Sorafenib | — | 300 |
| 4 | Vemurafenib | — | 298 |
| 5 | aniracetam | — | 110 |
| 6 | Nadolol | — | 297 |
| 7 | Nicardipine | — | 94 |
| 8 | Crizotinib | — | 298 |
About the TGFBR3 regulates TGF-beta signaling Pathway
The TGFBR3 regulates TGF-beta signaling pathway is catalogued in Reactome (ID: R-HSA-9839389) and involves 3 genes. In the BiohacksAI corpus, 8 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ARRB1, TGFBR1, TGFBR2.