Malate-aspartate shuttle
REACTOME PATHWAYThe Malate-aspartate shuttle pathway (Reactome ID: R-HSA-9856872) involves 1 genes and is affected by 1 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Malate-aspartate shuttle
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sorafenib | — | 300 |
About the Malate-aspartate shuttle Pathway
The Malate-aspartate shuttle pathway is catalogued in Reactome (ID: R-HSA-9856872) and involves 1 genes. In the BiohacksAI corpus, 1 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include MDH2.