Branched-chain ketoacid dehydrogenase kinase deficiency
REACTOME PATHWAYThe Branched-chain ketoacid dehydrogenase kinase deficiency pathway (Reactome ID: R-HSA-9912481) involves 1 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Branched-chain ketoacid dehydrogenase kinase deficiency
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | egcg | — | 300 |
| 2 | Rutin | — | 300 |
| 3 | Oxaprozin | — | 181 |
| 4 | Pioglitazone | — | 297 |
| 5 | streptonigrin | — | 299 |
About the Branched-chain ketoacid dehydrogenase kinase deficiency Pathway
The Branched-chain ketoacid dehydrogenase kinase deficiency pathway is catalogued in Reactome (ID: R-HSA-9912481) and involves 1 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include DLD.