Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome
REACTOME PATHWAYThe Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome pathway (Reactome ID: R-HSA-9944997) involves 4 genes and is affected by 1 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | s adenosylhomocysteine | — | 300 |
About the Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome Pathway
The Loss of Function of KMT2D in MLL4 Complex Formation in Kabuki Syndrome pathway is catalogued in Reactome (ID: R-HSA-9944997) and involves 4 genes. In the BiohacksAI corpus, 1 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ASH2L, DPY30, RBBP5, WDR5.