Lanosterol biosynthesis
REACTOME PATHWAYThe Lanosterol biosynthesis pathway (Reactome ID: R-HSA-9969896) involves 2 genes and is affected by 8 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Lanosterol biosynthesis
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Lovastatin | — | 300 |
| 2 | Simvastatin | — | 1,000 |
| 3 | Pravastatin | — | 297 |
| 4 | Atorvastatin | — | 1,000 |
| 5 | Artemether | — | 299 |
| 6 | Rosuvastatin Calcium | — | 216 |
| 7 | Isopentenyladenosine N(6)-[delta(3)-isopentenyl]adenosine. Isopentenyl derivative of adenosine which is | — | 270 |
| 8 | Zoledronic Acid | — | 299 |
About the Lanosterol biosynthesis Pathway
The Lanosterol biosynthesis pathway is catalogued in Reactome (ID: R-HSA-9969896) and involves 2 genes. In the BiohacksAI corpus, 8 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include FDPS, HMGCR.