ACVR1B
MOLECULAR TARGETactivin A receptor type 1B
ACVR1B (activin A receptor type 1B) is targeted by 25 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting ACVR1B
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | sb 203580 | 4.92 | 136 |
| 2 | doramapimod | 4.06 | 57 |
| 3 | sb 202190 | 3.64 | 37 |
| 4 | nintedanib | 3.61 | 36 |
| 5 | tae 684 | 3.43 | 30 |
| 6 | fedratinib | 3.40 | 29 |
| 7 | saracatinib | 3.33 | 27 |
| 8 | sb 431542 | 3.33 | 27 |
| 9 | dabrafenib | 3.30 | 26 |
| 10 | dorsomorphin | 3.14 | 22 |
| 11 | at 9283 | 3.09 | 21 |
| 12 | lestaurtinib | 3.04 | 20 |
| 13 | danusertib | 2.94 | 18 |
| 14 | galunisertib | 2.94 | 18 |
| 15 | r 406 | 2.83 | 16 |
| 16 | k 252a | 2.83 | 16 |
| 17 | cediranib | 2.83 | 16 |
| 18 | mk 5108 | 2.48 | 11 |
| 19 | vactosertib | 2.40 | 10 |
| 20 | gsk 1070916 | 2.20 | 8 |
| 21 | cyc 116 | 2.08 | 7 |
| 22 | osi 027 | 2.08 | 7 |
| 23 | osi 632 | 1.79 | 5 |
| 24 | Crizotinib | 0.69 | 1 |
| 25 | Dasatinib | 0.69 | 1 |
About ACVR1B as a Drug Target
ACVR1B (activin A receptor type 1B) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 25 compounds with documented ACVR1B interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
ACVR1B inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.