CAMK1
MOLECULAR TARGETcalcium/calmodulin dependent protein kinase I
CAMK1 (calcium/calmodulin dependent protein kinase I) is targeted by 19 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting CAMK1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | tofacitinib | 4.65 | 104 |
| 2 | foretinib | 4.34 | 76 |
| 3 | tozasertib | 4.33 | 75 |
| 4 | ruxolitinib | 4.23 | 68 |
| 5 | midostaurin | 3.85 | 46 |
| 6 | pazopanib | 3.69 | 39 |
| 7 | nintedanib | 3.61 | 36 |
| 8 | tae 684 | 3.43 | 30 |
| 9 | fedratinib | 3.40 | 29 |
| 10 | sp 600125 | 3.22 | 24 |
| 11 | lestaurtinib | 3.04 | 20 |
| 12 | r 406 | 2.83 | 16 |
| 13 | pha 665752 | 2.71 | 14 |
| 14 | plx 4720 | 2.71 | 14 |
| 15 | kw 2449 | 2.64 | 13 |
| 16 | ast 487 | 2.56 | 12 |
| 17 | su 014813 | 2.20 | 8 |
| 18 | pictilisib | 0.69 | 1 |
| 19 | sp600125 | 0.69 | 1 |
About CAMK1 as a Drug Target
CAMK1 (calcium/calmodulin dependent protein kinase I) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 19 compounds with documented CAMK1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
CAMK1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.