CDC42BPB
MOLECULAR TARGETCDC42 binding protein kinase beta
CDC42BPB (CDC42 binding protein kinase beta) is targeted by 17 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting CDC42BPB
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | sb 203580 | 4.92 | 136 |
| 2 | alvocidib | 4.52 | 91 |
| 3 | foretinib | 4.34 | 76 |
| 4 | vandetanib | 4.30 | 73 |
| 5 | nilotinib | 4.17 | 64 |
| 6 | doramapimod | 4.06 | 57 |
| 7 | sb 202190 | 3.64 | 37 |
| 8 | tae 684 | 3.43 | 30 |
| 9 | lestaurtinib | 3.04 | 20 |
| 10 | gsk 690693 | 2.64 | 13 |
| 11 | zotiraciclib | 2.56 | 12 |
| 12 | decernotinib | 2.20 | 8 |
| 13 | y 39983 | 2.20 | 8 |
| 14 | ucn 01 | 1.79 | 5 |
| 15 | sar 407899 free base | 1.79 | 5 |
| 16 | Axitinib | 0.69 | 1 |
| 17 | Dasatinib | 0.69 | 1 |
About CDC42BPB as a Drug Target
CDC42BPB (CDC42 binding protein kinase beta) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 17 compounds with documented CDC42BPB interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
CDC42BPB inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.