CHUK
MOLECULAR TARGETcomponent of inhibitor of nuclear factor kappa B kinase complex
CHUK (component of inhibitor of nuclear factor kappa B kinase complex) is targeted by 18 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting CHUK
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | foretinib | 4.34 | 76 |
| 2 | pi 103 | 4.17 | 64 |
| 3 | midostaurin | 3.85 | 46 |
| 4 | norharmane | 3.76 | 42 |
| 5 | nintedanib | 3.61 | 36 |
| 6 | fedratinib | 3.40 | 29 |
| 7 | dovitinib | 3.09 | 21 |
| 8 | lestaurtinib | 3.04 | 20 |
| 9 | r 406 | 2.83 | 16 |
| 10 | imd 0354 | 2.83 | 16 |
| 11 | bms 345541 | 2.71 | 14 |
| 12 | kw 2449 | 2.64 | 13 |
| 13 | ast 487 | 2.56 | 12 |
| 14 | as 602868 | 2.56 | 12 |
| 15 | su 014813 | 2.20 | 8 |
| 16 | gsk 625137a | 1.79 | 5 |
| 17 | glaucarubinone | 1.10 | 2 |
| 18 | chicoric acid | 0.69 | 1 |
About CHUK as a Drug Target
CHUK (component of inhibitor of nuclear factor kappa B kinase complex) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 18 compounds with documented CHUK interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
CHUK inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.