CISD1
MOLECULAR TARGETCDGSH iron sulfur domain 1
CISD1 (CDGSH iron sulfur domain 1) is targeted by 9 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting CISD1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Pioglitazone | 1.39 | 3 |
| 2 | Kaempferols | 1.10 | 2 |
| 3 | Adenosine Triphosphate | 0.69 | 1 |
| 4 | Dantrolene Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in | 0.69 | 1 |
| 5 | Furosemide | 0.69 | 1 |
| 6 | Gemfibrozil | 0.69 | 1 |
| 7 | Glyburide | 0.69 | 1 |
| 8 | Nitrofurantoin | 0.69 | 1 |
| 9 | Ursodeoxycholic Acid | 0.69 | 1 |
About CISD1 as a Drug Target
CISD1 (CDGSH iron sulfur domain 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 9 compounds with documented CISD1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
CISD1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.