What compounds target CNR2?

BiohacksAI has identified 356 compounds that interact with CNR2 (cannabinoid receptor 2). Top compounds include: epigalocatechin gallate, win 552122, cp 55940, dronabinol, Rimonabant. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is CNR2 (cannabinoid receptor 2)?

CNR2 is cannabinoid receptor 2. It is a molecular target for 356 compounds documented in PubMed bioassay data. UniProt ID: P34972. NCBI Gene ID: 1269.

CNR2

MOLECULAR TARGET

cannabinoid receptor 2

UniProt: P34972 NCBI Gene: 1269356 compounds

CNR2 (cannabinoid receptor 2) is targeted by 356 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting CNR2

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	epigalocatechin gallate	5.40	220
2	win 552122	4.72	111
3	cp 55940	4.70	109
4	dronabinol	4.53	92
5	Rimonabant	4.28	71
6	honokiol	4.17	64
7	anandamide	4.16	63
8	epicatechin gallate	3.95	51
9	magnolol	3.78	43
10	sr 144528	3.64	37
11	cbd	3.40	29
12	cannabidiol	3.40	29
13	delta 8 tetrahydrocannabinol	3.14	22
14	taranabant	3.04	20
15	cannabinol	2.89	17
16	cannabigerol	2.71	14
17	2 arachidonoylglycerol	2.71	14
18	methylhonokiol	2.71	14
19	ibipinabant	2.64	13
20	cannabidivarin	2.56	12
21	beta caryophyllene	2.56	12
22	cannabichromene	2.48	11
23	methanandamide	2.40	10
24	nabilone	2.30	9
25	guineensine	2.30	9
26	tetrahydrocannabivarin	2.20	8
27	rac ibipinabant	2.20	8
28	emindole sb	2.20	8
29	delta9 tetrahydrocannabinolic acid a	2.08	7
30	dexanabinol	2.08	7
31	otenabant	1.95	6
32	rimonabant hydrochloride	1.79	5
33	lenabasum	1.79	5
34	bdb chembl2414015	1.10	2
35	bdb chembl2414016	1.10	2
36	bdb chembl2414017	1.10	2
37	bdb chembl2414018	1.10	2
38	bdb chembl2414019	1.10	2
39	bdb chembl2414020	1.10	2
40	bdb chembl2414022	1.10	2
41	bdb chembl2414023	1.10	2
42	bdb chembl2414026	1.10	2
43	bdb chembl2414027	1.10	2
44	bdb chembl2414029	1.10	2
45	bdb n adamant 1 yl 4 oxo 1 pentyl 6 phenyl 1 4 dihydroquinoline 3 carboxamide chembl	1.10	2
46	bdb n adamant 1 yl 6 isopropyl 4 oxo 1 pentyl 1 4 dihydroquinoline 3 carboxamide 6 i	1.10	2
47	bdb n3 1 adamantyl 4 oxo 1 pentyl 1 4 dihydroquinoline 3 carboxamide 4 oxo 1 pentyl	1.10	2
48	bdb n3 1 adamantyl methyl 4 oxo 1 pentyl 1 4 dihydroquinoline 3 carboxamide chembl23	1.10	2
49	N-pyridazin-3-yl-4-(3-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzylidene)piperidine-1-carboxamide [Supplementary Concept]	0.69	1
50	bdb 1 1 adamantylcarbonyl 4 2 4 dichlorophenyl phenyl methyl piperazine chembl109569	0.69	1

Showing top 50 of 356 compounds. Use the BiohacksAI search to explore all CNR2 modulators.

About CNR2 as a Drug Target

CNR2 (cannabinoid receptor 2) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 356 compounds with documented CNR2 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

CNR2 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.