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BiohacksAI

Evidence-Based Biohacking

Patent Pending

DYRK1A

MOLECULAR TARGET

dual specificity tyrosine phosphorylation regulated kinase 1A

UniProt: Q63470NCBI Gene: 2525513 compounds

DYRK1A (dual specificity tyrosine phosphorylation regulated kinase 1A) is targeted by 13 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting DYRK1A

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#CompoundConfidenceActive Assays
1Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is1.956
2Kaempferols1.102
3calycosin1.102
4Dichlororibofuranosylbenzimidazole1.102
5Harmaline1.102
6piceatannol1.102
7egcg0.691
8Luteolin 5,7,3',4'-tetrahydroxy-flavone,0.691
9myricetin-3-O-galactopyranoside [Supplementary Concept]0.691
10Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as0.691
11kenpaullone0.691
12Salmeterol Xinafoate0.691
13sp6001250.691

About DYRK1A as a Drug Target

DYRK1A (dual specificity tyrosine phosphorylation regulated kinase 1A) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 13 compounds with documented DYRK1A interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

DYRK1A inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.