ELANE
MOLECULAR TARGETelastase, neutrophil expressed
ELANE (elastase, neutrophil expressed) is targeted by 14 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting ELANE
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | epigalocatechin gallate | 5.40 | 220 |
| 2 | telaprevir | 4.09 | 59 |
| 3 | boceprevir | 4.09 | 59 |
| 4 | amentoflavone | 3.76 | 42 |
| 5 | sirtinol | 3.43 | 30 |
| 6 | phenylmethylsulfonylfluoride | 3.33 | 27 |
| 7 | sivelestat | 3.00 | 19 |
| 8 | nymphaeol a | 2.64 | 13 |
| 9 | robustaflavone | 2.48 | 11 |
| 10 | delanzomib | 2.08 | 7 |
| 11 | archazolid a | 1.95 | 6 |
| 12 | lyngbyastatin 7 | 1.79 | 5 |
| 13 | Ursolic Acid | 0.69 | 1 |
| 14 | Bortezomib | 0.69 | 1 |
About ELANE as a Drug Target
ELANE (elastase, neutrophil expressed) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 14 compounds with documented ELANE interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
ELANE inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.