GRIK1
MOLECULAR TARGETglutamate ionotropic receptor kainate type subunit 1
GRIK1 (glutamate ionotropic receptor kainate type subunit 1) is targeted by 9 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting GRIK1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | kainic acid | 3.81 | 44 |
| 2 | nbqx | 3.56 | 34 |
| 3 | s ampa | 3.00 | 19 |
| 4 | rs ampa | 3.00 | 19 |
| 5 | Glutamic Acid | 2.77 | 15 |
| 6 | Glutamic Acid | 2.77 | 15 |
| 7 | tezampanel anhydrous | 2.71 | 14 |
| 8 | 2s4r 4 methylglutamate | 2.08 | 7 |
| 9 | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid | 1.61 | 4 |
About GRIK1 as a Drug Target
GRIK1 (glutamate ionotropic receptor kainate type subunit 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 9 compounds with documented GRIK1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
GRIK1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.