METTL3
MOLECULAR TARGETmethyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit
METTL3 (methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit) is targeted by 5 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting METTL3
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | meclofenamic acid | 3.50 | 32 |
| 2 | eltrombopag | 2.64 | 13 |
| 3 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 0.69 | 1 |
| 4 | Quercetin | 0.69 | 1 |
| 5 | s adenosylhomocysteine | 0.69 | 1 |
About METTL3 as a Drug Target
METTL3 (methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 5 compounds with documented METTL3 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
METTL3 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.