NEK7
MOLECULAR TARGETNIMA related kinase 7
NEK7 (NIMA related kinase 7) is targeted by 15 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting NEK7
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | berberine chloride | 4.56 | 95 |
| 2 | tozasertib | 4.33 | 75 |
| 3 | ruxolitinib | 4.23 | 68 |
| 4 | bi 2536 | 4.01 | 54 |
| 5 | tae 684 | 3.43 | 30 |
| 6 | fedratinib | 3.40 | 29 |
| 7 | dovitinib | 3.09 | 21 |
| 8 | lestaurtinib | 3.04 | 20 |
| 9 | r 406 | 2.83 | 16 |
| 10 | k 252a | 2.83 | 16 |
| 11 | kw 2449 | 2.64 | 13 |
| 12 | gsk 690693 | 2.64 | 13 |
| 13 | bms 754807 | 2.30 | 9 |
| 14 | su 014813 | 2.20 | 8 |
| 15 | Crizotinib | 0.69 | 1 |
About NEK7 as a Drug Target
NEK7 (NIMA related kinase 7) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 15 compounds with documented NEK7 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
NEK7 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.