NEK9
MOLECULAR TARGETNIMA related kinase 9
NEK9 (NIMA related kinase 9) is targeted by 21 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting NEK9
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | foretinib | 4.34 | 76 |
| 2 | tae 684 | 3.43 | 30 |
| 3 | fedratinib | 3.40 | 29 |
| 4 | dabrafenib | 3.30 | 26 |
| 5 | dovitinib | 3.09 | 21 |
| 6 | at 9283 | 3.09 | 21 |
| 7 | lestaurtinib | 3.04 | 20 |
| 8 | pacritinib | 3.04 | 20 |
| 9 | danusertib | 2.94 | 18 |
| 10 | momelotinib | 2.89 | 17 |
| 11 | r 406 | 2.83 | 16 |
| 12 | milciclib | 2.77 | 15 |
| 13 | enmd 2076 | 2.71 | 14 |
| 14 | kw 2449 | 2.64 | 13 |
| 15 | ast 487 | 2.56 | 12 |
| 16 | gsk 461364 | 2.40 | 10 |
| 17 | bms 754807 | 2.30 | 9 |
| 18 | rebastinib | 2.20 | 8 |
| 19 | cyc 116 | 2.08 | 7 |
| 20 | fostamatinib | 2.08 | 7 |
| 21 | Crizotinib | 0.69 | 1 |
About NEK9 as a Drug Target
NEK9 (NIMA related kinase 9) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 21 compounds with documented NEK9 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
NEK9 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.