PDE1A
MOLECULAR TARGETphosphodiesterase 1A
PDE1A (phosphodiesterase 1A) is targeted by 7 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PDE1A
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | sildenafil | 4.78 | 118 |
| 2 | nimodipine | 4.29 | 72 |
| 3 | crisaborole | 2.71 | 14 |
| 4 | berbamine | 2.30 | 9 |
| 5 | edelinontrine | 2.20 | 8 |
| 6 | vinpocetine | 0.69 | 1 |
| 7 | Papaverine | 0.69 | 1 |
About PDE1A as a Drug Target
PDE1A (phosphodiesterase 1A) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 7 compounds with documented PDE1A interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PDE1A inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.