PDE4C
MOLECULAR TARGETphosphodiesterase 4C
PDE4C (phosphodiesterase 4C) is targeted by 11 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PDE4C
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | rolipram | 5.12 | 166 |
| 2 | roflumilast | 4.04 | 56 |
| 3 | cilomilast | 3.71 | 40 |
| 4 | piclamilast | 3.04 | 20 |
| 5 | rolipram | 2.83 | 16 |
| 6 | crisaborole | 2.71 | 14 |
| 7 | cdp840 | 2.71 | 14 |
| 8 | ibudilast | 2.48 | 11 |
| 9 | Enoximone | 1.10 | 2 |
| 10 | 8-Bromo Cyclic Adenosine Monophosphate | 0.69 | 1 |
| 11 | streptonigrin | 0.69 | 1 |
About PDE4C as a Drug Target
PDE4C (phosphodiesterase 4C) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 11 compounds with documented PDE4C interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PDE4C inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.