What compounds target PDGFRB?

BiohacksAI has identified 85 compounds that interact with PDGFRB (platelet derived growth factor receptor beta). Top compounds include: erlotinib, imatinib, lapatinib, foretinib, tozasertib. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is PDGFRB (platelet derived growth)?

PDGFRB is platelet derived growth factor receptor beta. It is a molecular target for 85 compounds documented in PubMed bioassay data. UniProt ID: P09619. NCBI Gene ID: 5159.

PDGFRB

MOLECULAR TARGET

platelet derived growth factor receptor beta

UniProt: P09619 NCBI Gene: 515985 compounds

PDGFRB (platelet derived growth factor receptor beta) is targeted by 85 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting PDGFRB

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	erlotinib	5.55	256
2	imatinib	5.47	236
3	lapatinib	4.84	126
4	foretinib	4.34	76
5	tozasertib	4.33	75
6	vandetanib	4.30	73
7	ponatinib	4.26	70
8	nilotinib	4.17	64
9	bosutinib	4.08	58
10	doramapimod	4.06	57
11	quizartinib	3.99	53
12	semaxanib	3.93	50
13	midostaurin	3.85	46
14	pazopanib	3.69	39
15	vatalanib	3.69	39
16	nintedanib	3.61	36
17	regorafenib	3.56	34
18	canertinib	3.53	33
19	tae 684	3.43	30
20	pexidartinib	3.43	30
21	fedratinib	3.40	29
22	gilteritinib	3.40	29
23	linifanib	3.33	27
24	saracatinib	3.33	27
25	neflamapimod	3.30	26
26	sgi 1776	3.26	25
27	tandutinib	3.22	24
28	Sorafenib	3.14	22
29	dovitinib	3.09	21
30	jnj 7706621	3.09	21
31	lestaurtinib	3.04	20
32	pacritinib	3.04	20
33	lenvatinib	3.04	20
34	pf 03758309	3.00	19
35	ruboxistaurin	2.94	18
36	ci 1040	2.94	18
37	defosbarasertib	2.89	17
38	orantinib	2.89	17
39	barasertib	2.89	17
40	r 406	2.83	16
41	k 252a	2.83	16
42	cediranib	2.83	16
43	su 9516	2.83	16
44	milciclib	2.77	15
45	masitinib	2.77	15
46	pha 665752	2.71	14
47	plx 4720	2.71	14
48	crenolanib	2.71	14
49	kw 2449	2.64	13
50	gsk 690693	2.64	13

Showing top 50 of 85 compounds. Use the BiohacksAI search to explore all PDGFRB modulators.

About PDGFRB as a Drug Target

PDGFRB (platelet derived growth factor receptor beta) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 85 compounds with documented PDGFRB interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

PDGFRB inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.