PIK3C2B
MOLECULAR TARGETphosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
PIK3C2B (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta) is targeted by 18 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PIK3C2B
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | ly 294002 | 4.84 | 126 |
| 2 | lapatinib | 4.84 | 126 |
| 3 | dactolisib | 4.25 | 69 |
| 4 | pi 103 | 4.17 | 64 |
| 5 | midostaurin | 3.85 | 46 |
| 6 | zstk 474 | 3.56 | 34 |
| 7 | buparlisib | 3.40 | 29 |
| 8 | lestaurtinib | 3.04 | 20 |
| 9 | apitolisib | 2.71 | 14 |
| 10 | gedatolisib | 2.56 | 12 |
| 11 | gsk 461364 | 2.40 | 10 |
| 12 | torin1 | 2.40 | 10 |
| 13 | bimiralisib | 2.30 | 9 |
| 14 | pictilisib | 2.20 | 8 |
| 15 | tg100 115 | 2.08 | 7 |
| 16 | gsk 2636771 | 2.08 | 7 |
| 17 | ly294002 | 1.79 | 5 |
| 18 | torin 1 | 1.10 | 2 |
About PIK3C2B as a Drug Target
PIK3C2B (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 18 compounds with documented PIK3C2B interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PIK3C2B inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.