PIN1
MOLECULAR TARGETpeptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIN1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1) is targeted by 6 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PIN1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | epigalocatechin gallate | 5.40 | 220 |
| 2 | tretinoin | 5.16 | 174 |
| 3 | naphthoquinone | 3.58 | 35 |
| 4 | akba | 2.89 | 17 |
| 5 | juglone hydroxylase [Supplementary Concept] catalyzes | 1.10 | 2 |
| 6 | Aurintricarboxylic Acid | 0.69 | 1 |
About PIN1 as a Drug Target
PIN1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 6 compounds with documented PIN1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PIN1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.