PKLR
MOLECULAR TARGETpyruvate kinase L/R
PKLR (pyruvate kinase L/R) is targeted by 3 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting PKLR
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | shikonin | 4.11 | 60 |
| 2 | alizarin red s | 1.79 | 5 |
| 3 | Suramin | 1.10 | 2 |
About PKLR as a Drug Target
PKLR (pyruvate kinase L/R) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 3 compounds with documented PKLR interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
PKLR inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.