What compounds target STK10?

BiohacksAI has identified 75 compounds that interact with STK10 (serine/threonine kinase 10). Top compounds include: gefitinib, erlotinib, lapatinib, foretinib, tozasertib. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is STK10 (serine/threonine kinase 10)?

STK10 is serine/threonine kinase 10. It is a molecular target for 75 compounds documented in PubMed bioassay data. UniProt ID: O94804. NCBI Gene ID: 6793.

STK10

MOLECULAR TARGET

serine/threonine kinase 10

UniProt: O94804 NCBI Gene: 679375 compounds

STK10 (serine/threonine kinase 10) is targeted by 75 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting STK10

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	gefitinib	5.67	290
2	erlotinib	5.55	256
3	lapatinib	4.84	126
4	foretinib	4.34	76
5	tozasertib	4.33	75
6	vandetanib	4.30	73
7	nilotinib	4.17	64
8	bosutinib	4.08	58
9	doramapimod	4.06	57
10	bi 2536	4.01	54
11	quizartinib	3.99	53
12	midostaurin	3.85	46
13	brigatinib	3.81	44
14	silmitasertib	3.78	43
15	pazopanib	3.69	39
16	neratinib	3.66	38
17	abemaciclib	3.66	38
18	nintedanib	3.61	36
19	canertinib	3.53	33
20	pelitinib	3.50	32
21	tae 684	3.43	30
22	fedratinib	3.40	29
23	gilteritinib	3.40	29
24	linifanib	3.33	27
25	mln 8054	3.33	27
26	saracatinib	3.33	27
27	sgi 1776	3.26	25
28	tandutinib	3.22	24
29	bisindolylmaleimide ix	3.14	22
30	dovitinib	3.09	21
31	jnj 7706621	3.09	21
32	at 9283	3.09	21
33	lestaurtinib	3.04	20
34	pacritinib	3.04	20
35	lenvatinib	3.04	20
36	filgotinib	3.04	20
37	ruboxistaurin	2.94	18
38	danusertib	2.94	18
39	defosbarasertib	2.89	17
40	r 406	2.83	16
41	k 252a	2.83	16
42	cediranib	2.83	16
43	pha 665752	2.71	14
44	crenolanib	2.71	14
45	apitolisib	2.71	14
46	kw 2449	2.64	13
47	tivozanib	2.64	13
48	ast 487	2.56	12
49	zotiraciclib	2.56	12
50	raf 265	2.48	11

Showing top 50 of 75 compounds. Use the BiohacksAI search to explore all STK10 modulators.

About STK10 as a Drug Target

STK10 (serine/threonine kinase 10) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 75 compounds with documented STK10 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

STK10 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.