TDP2
MOLECULAR TARGETtyrosyl-DNA phosphodiesterase 2
TDP2 (tyrosyl-DNA phosphodiesterase 2) is targeted by 7 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting TDP2
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | lapachone | 4.34 | 76 |
| 2 | lmp 744 | 2.64 | 13 |
| 3 | 910 phenanthrenequinone | 2.30 | 9 |
| 4 | Calcimycin | 0.69 | 1 |
| 5 | Edaravone | 0.69 | 1 |
| 6 | Ethidium | 0.69 | 1 |
| 7 | Ethoxyquin Antioxidant; also | 0.69 | 1 |
About TDP2 as a Drug Target
TDP2 (tyrosyl-DNA phosphodiesterase 2) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 7 compounds with documented TDP2 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
TDP2 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.