What compounds target TEK?

BiohacksAI has identified 45 compounds that interact with TEK (TEK receptor tyrosine kinase). Top compounds include: cabozantinib, foretinib, tozasertib, vandetanib, nilotinib. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is TEK (TEK receptor tyrosine)?

TEK is TEK receptor tyrosine kinase. It is a molecular target for 45 compounds documented in PubMed bioassay data. UniProt ID: Q02763. NCBI Gene ID: 7010.

TEK

MOLECULAR TARGET

TEK receptor tyrosine kinase

UniProt: Q02763 NCBI Gene: 701045 compounds

TEK (TEK receptor tyrosine kinase) is targeted by 45 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting TEK

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	cabozantinib	4.39	80
2	foretinib	4.34	76
3	tozasertib	4.33	75
4	vandetanib	4.30	73
5	nilotinib	4.17	64
6	bosutinib	4.08	58
7	doramapimod	4.06	57
8	bi 2536	4.01	54
9	quizartinib	3.99	53
10	loperamide	3.93	50
11	midostaurin	3.85	46
12	pazopanib	3.69	39
13	neratinib	3.66	38
14	nintedanib	3.61	36
15	regorafenib	3.56	34
16	pelitinib	3.50	32
17	tae 684	3.43	30
18	fedratinib	3.40	29
19	linifanib	3.33	27
20	mln 8054	3.33	27
21	sulfuretin	3.14	22
22	jnj 7706621	3.09	21
23	lestaurtinib	3.04	20
24	defosbarasertib	2.89	17
25	r 406	2.83	16
26	cediranib	2.83	16
27	infigratinib	2.77	15
28	pha 665752	2.71	14
29	kw 2449	2.64	13
30	tivozanib	2.64	13
31	ast 487	2.56	12
32	raf 265	2.48	11
33	brivanib	2.48	11
34	Sorafenib	2.40	10
35	bms 754807	2.30	9
36	rebastinib	2.20	8
37	gsk 1070916	2.20	8
38	maleimide	1.95	6
39	bastadin 7	1.95	6
40	osi 632	1.79	5
41	gw770249x	1.79	5
42	Crizotinib	1.61	4
43	Ampicillin Semi-synthetic derivative of penicillin that functions as	0.69	1
44	Axitinib	0.69	1
45	Cetirizine	0.69	1

About TEK as a Drug Target

TEK (TEK receptor tyrosine kinase) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 45 compounds with documented TEK interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

TEK inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.