What compounds target TYR?

BiohacksAI has identified 25 compounds that interact with TYR (tyrosinase). Top compounds include: kojic acid, Butylated Hydroxytoluene, coumaric acid, paraben, hydroquinone. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is TYR (tyrosinase)?

TYR is tyrosinase. It is a molecular target for 25 compounds documented in PubMed bioassay data. UniProt ID: P14679. NCBI Gene ID: 7299.

TYR

MOLECULAR TARGET

tyrosinase

UniProt: P14679 NCBI Gene: 729925 compounds

TYR (tyrosinase) is targeted by 25 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting TYR

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	kojic acid	5.27	194
2	Butylated Hydroxytoluene	4.93	137
3	coumaric acid	4.42	82
4	paraben	4.17	64
5	hydroquinone	3.95	51
6	e319	3.85	46
7	oxyresveratrol	3.04	20
8	3 hydroxycoumarin	2.94	18
9	hinokitiol	2.89	17
10	methyl p hydroxycinnamate	2.77	15
11	glabridin	2.71	14
12	xanthone	2.64	13
13	moracin m	2.56	12
14	norartocarpetin	2.40	10
15	hexylresorcinol	2.40	10
16	l mimosine	2.30	9
17	morachalcone a	2.20	8
18	n trans feruloyldopamine	2.08	7
19	34 dihydroxyxanthone	1.95	6
20	arbutin	1.79	5
21	Phenylthiourea Phenylthiourea is	1.61	4
22	chrysin	0.69	1
23	Kaempferols	0.69	1
24	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	0.69	1
25	Mimosine 3-Hydroxy-4-oxo-1(4H)-pyridinealanine.	0.69	1

About TYR as a Drug Target

TYR (tyrosinase) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 25 compounds with documented TYR interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

TYR inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.