BiohacksAI/Mechanism Hypothesis/Adenosine

Adenosine — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

ESR1CHAINNSD2RORCHISTONE-LYSINEHOMOHTR2ANTMT1RXRAADORA3ADENOSINEMRGPRX1ADORA1SLC5A7GALR3HOXA9SLC29A1TRPM4ADORA2AMAP3K7PI4K2AADKADORA2BADATLR4TMIGD3AHCYSLC28A1SLC28A2SLC28A3SLC29A2PI4K2B

32 known targets mapped from PubChem bioassay data

Pathway Context

Drug ADME5 targets overlapping

SLC-mediated transmembrane transport5 targets overlapping

Ribavirin ADME5 targets overlapping

Uncovered Pathway Targets

232 total

ABCB1ABCC1ABCC2ABCC3ABCC4ABCC5ABCG2AKR1C1ALBBCHE+222 more…

Genes present in the top pathway union that Adenosine does not directly modulate.

Top Stack Candidates

Fluoxetine

#1 gap-filler · 28 targets covered · evidence score 73.4

score 7,966.259

CYP2C19CYP2D6CYP3A4SLC29A4SLC6A2SLC6A3SLC6A4ADRA1AADRA1BADRA1DADRA2AADRA2B+16

Aripiprazole

#2 gap-filler · 36 targets covered · evidence score 52.0

score 7,092.281

ABCB1CYP2C9CYP2D6SLC6A2SLC6A3SLC6A4ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2C+24

967 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.