Dihydroergotoxine — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
TDP1DRD3HTR2ADRD1HTR5AFASNSIAE
7 known targets mapped from PubChem bioassay data
Pathway Context
Class A/1 (Rhodopsin-like receptors)3 targets overlapping
Amine ligand-binding receptors3 targets overlapping
Dopamine receptors2 targets overlapping
Uncovered Pathway Targets
143 totalADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2+133 more…
Genes present in the top pathway union that Dihydroergotoxine does not directly modulate.
Top Stack Candidates
Aripiprazole
score 6,085.404#1 gap-filler · 29 targets covered · evidence score 52.0
ADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1AVPR1A+17
Fluoxetine
score 6,039.032#2 gap-filler · 20 targets covered · evidence score 73.4
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CCCKBRCHRM3CHRM5CNR1DRD2EDNRA+8
611 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.