Leukotriene D4 — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
ABCC2RGS4CYSLTR1CYSLTR2
4 known targets mapped from PubChem bioassay data
Pathway Context
G alpha (q) signalling events3 targets overlapping
Class A/1 (Rhodopsin-like receptors)2 targets overlapping
Leishmania infection2 targets overlapping
Uncovered Pathway Targets
202 totalADRA1AADRA1BADRA1DAGTR1APPAVPR1AAVPR1BBDKRB1BDKRB2BTK+192 more…
Genes present in the top pathway union that Leukotriene D4 does not directly modulate.
Top Stack Candidates
Aripiprazole
score 6,972.342#1 gap-filler · 34 targets covered · evidence score 52.0
ADRA1AADRA1BADRA1DAGTR1AVPR1ACHRM1GNA15HRH1HTR2AHTR2BHTR2CMLNR+22
Fluoxetine
score 6,913.557#2 gap-filler · 24 targets covered · evidence score 73.4
ADRA1AADRA1BADRA1DCCKBRCHRM3CHRM5EDNRAHRH1HTR2AHTR2BHTR2CADRA2A+12
799 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.