Apoptotic cleavage of cellular proteins
REACTOME PATHWAYThe Apoptotic cleavage of cellular proteins pathway (Reactome ID: R-HSA-111465) involves 4 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Apoptotic cleavage of cellular proteins
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Crizotinib | — | 298 |
| 2 | Dasatinib | — | 299 |
| 3 | Lovastatin | — | 300 |
| 4 | Gliotoxin | — | 300 |
| 5 | Histamine | — | 300 |
About the Apoptotic cleavage of cellular proteins Pathway
The Apoptotic cleavage of cellular proteins pathway is catalogued in Reactome (ID: R-HSA-111465) and involves 4 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include BMX, FNTA, LMNA, STK26.