Cross-presentation of particulate exogenous antigens (phagosomes)
REACTOME PATHWAYThe Cross-presentation of particulate exogenous antigens (phagosomes) pathway (Reactome ID: R-HSA-1236973) involves 3 genes and is affected by 9 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Cross-presentation of particulate exogenous antigens (phagosomes)
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | — | 150 |
| 2 | Apigenin 5,7,4'-trihydroxy-flavone, | — | 300 |
| 3 | chrysin | — | 300 |
| 4 | celastrol | — | 300 |
| 5 | Naloxone | — | 299 |
| 6 | Methylene Blue | — | 200 |
| 7 | indirubin | — | 300 |
| 8 | Loxapine | — | 30 |
| 9 | Tirofiban Tyrosine analog and PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX antagonist that inhibits PLATELET AGGREGATION and is used in | — | 299 |
About the Cross-presentation of particulate exogenous antigens (phagosomes) Pathway
The Cross-presentation of particulate exogenous antigens (phagosomes) pathway is catalogued in Reactome (ID: R-HSA-1236973) and involves 3 genes. In the BiohacksAI corpus, 9 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CYBB, ITGAV, NCF1.