BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B
○

Celastrol

celastrol [Supplementary Concept] isolated from Tripterygium wilfordii; potent inhibitory activity on both Kir2.1 and ERG1 potassium channels, leading to LONG QT SYNDROME

300+ PubMed studies analyzed · Evidence Score: 37.9

Research Domains

Celastrol has been studied across 23 research domains including 🔬 Oncology, 🔬 Inflammation, 🫁 Liver & Detox, 🔥 Metabolic, ⚡ Energy & Fatigue. The primary research focus is 🔬 Oncology with 37% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Celastrol, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Topotecan
14 shared targets
cycloheximide
18 shared targets
Camptothecin
17 shared targets
Tripterygium
13 shared targets
Mycophenolic
12 shared targets
Thapsigargin
10 shared targets
withaferin
10 shared targets
Dactinomycin
13 shared targets
Deslanoside
10 shared targets
triolimus
12 shared targets
Loading evidence profile...

This evidence profile for Celastrol is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.