TWIK-releated acid-sensitive K+ channel (TASK)
REACTOME PATHWAYThe TWIK-releated acid-sensitive K+ channel (TASK) pathway (Reactome ID: R-HSA-1299316) involves 1 genes and is affected by 9 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting TWIK-releated acid-sensitive K+ channel (TASK)
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | auraptene | — | 148 |
| 2 | Clotrimazole | — | 296 |
| 3 | Arachidonic Acid | — | 245 |
| 4 | 17 alpha-Hydroxyprogesterone Caproate Hydroxyprogesterone derivative that acts as | — | 287 |
| 5 | Bisphenol A-Glycidyl Methacrylate | — | 197 |
| 6 | Fluoxymesterone | — | 278 |
| 7 | Miconazole | — | 298 |
| 8 | Oxyphenbutazone | — | 300 |
| 9 | Testosterone Propionate | — | 300 |
About the TWIK-releated acid-sensitive K+ channel (TASK) Pathway
The TWIK-releated acid-sensitive K+ channel (TASK) pathway is catalogued in Reactome (ID: R-HSA-1299316) and involves 1 genes. In the BiohacksAI corpus, 9 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include KCNK3.