Mitochondrial iron-sulfur cluster biogenesis
REACTOME PATHWAYThe Mitochondrial iron-sulfur cluster biogenesis pathway (Reactome ID: R-HSA-1362409) involves 1 genes and is affected by 7 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Mitochondrial iron-sulfur cluster biogenesis
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Demeclocycline | — | 5 |
| 2 | Dinitrochlorobenzene | — | 300 |
| 3 | kenpaullone | — | 8 |
| 4 | Vorinostat | — | 299 |
| 5 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | — | 150 |
| 6 | Disulfiram | — | 297 |
| 7 | Vanillic Acid | — | 300 |
About the Mitochondrial iron-sulfur cluster biogenesis Pathway
The Mitochondrial iron-sulfur cluster biogenesis pathway is catalogued in Reactome (ID: R-HSA-1362409) and involves 1 genes. In the BiohacksAI corpus, 7 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include FXN.