A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
Disulfiram has been studied across 10 research domains including 🫁 Liver & Detox, 🌤️ Mood & Depression, 🧠 Focus & Attention, 🔬 Oncology, ❤️ Cardiovascular. The primary research focus is 🫁 Liver & Detox with 12% of studies addressing this area.
The following compounds share molecular targets with Disulfiram, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Disulfiram is generated deterministically from 297 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.