Regulation of signaling by NODAL
REACTOME PATHWAYThe Regulation of signaling by NODAL pathway (Reactome ID: R-HSA-1433617) involves 3 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Regulation of signaling by NODAL
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Dasatinib | — | 299 |
| 2 | Axitinib | — | 298 |
| 3 | Crizotinib | — | 298 |
About the Regulation of signaling by NODAL Pathway
The Regulation of signaling by NODAL pathway is catalogued in Reactome (ID: R-HSA-1433617) and involves 3 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ACVR1B, ACVR2A, ACVR2B.