Beta defensins
REACTOME PATHWAYThe Beta defensins pathway (Reactome ID: R-HSA-1461957) involves 2 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Beta defensins
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Calcimycin | — | 216 |
| 2 | Disulfiram | — | 297 |
| 3 | Oxyphenbutazone | — | 300 |
| 4 | Sphingosine | — | 300 |
| 5 | Myristic Acid | — | 300 |
| 6 | Palmitic Acid | — | 300 |
About the Beta defensins Pathway
The Beta defensins pathway is catalogued in Reactome (ID: R-HSA-1461957) and involves 2 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CCR6, TLR2.