Elastic fibre formation
REACTOME PATHWAYThe Elastic fibre formation pathway (Reactome ID: R-HSA-1566948) involves 7 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Elastic fibre formation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Disulfiram | — | 297 |
| 2 | Tirofiban Tyrosine analog and PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX antagonist that inhibits PLATELET AGGREGATION and is used in | — | 299 |
| 3 | 1-Deoxynojirimycin | — | 299 |
| 4 | Diminazene | — | 300 |
| 5 | silver sulfadiazine | — | 299 |
About the Elastic fibre formation Pathway
The Elastic fibre formation pathway is catalogued in Reactome (ID: R-HSA-1566948) and involves 7 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include FURIN, ITGAV, ITGB3, LOX, LOXL2.