Synthesis of PIPs at the early endosome membrane
REACTOME PATHWAYThe Synthesis of PIPs at the early endosome membrane pathway (Reactome ID: R-HSA-1660516) involves 4 genes and is affected by 8 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Synthesis of PIPs at the early endosome membrane
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Adenosine | — | 298 |
| 2 | torin 1 | — | 10 |
| 3 | pictilisib | — | 25 |
| 4 | piceatannol | — | 300 |
| 5 | Aurintricarboxylic Acid | — | 184 |
| 6 | Gemfibrozil | — | 297 |
| 7 | Iodoacetamide | — | 300 |
| 8 | Wortmannin | — | 300 |
About the Synthesis of PIPs at the early endosome membrane Pathway
The Synthesis of PIPs at the early endosome membrane pathway is catalogued in Reactome (ID: R-HSA-1660516) and involves 4 genes. In the BiohacksAI corpus, 8 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include PI4K2A, PI4K2B, PIK3C2A, PIK3C3.