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Wortmannin

An androstadiene metabolite produced by the fungi PENICILLIUM funiculosum that inhibits PHOSPHATIDYLINOSITOL-3-KINASES and alloantigen-specific activation of T-LYMPHOCYTES in human tumor cell lines. It is widely used in CELL BIOLOGY research and has broad therapeutic potential.

300+ PubMed studies analyzed · Evidence Score: 39.1

Research Domains

Wortmannin has been studied across 21 research domains including 🔬 Oncology, 🧬 Hormones, 🦴 Bone & Joint, 🔥 Metabolic, 🔬 Inflammation. The primary research focus is 🔬 Oncology with 30% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Wortmannin, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

buparlisib
9 shared targets
ly294002
15 shared targets
bimiralisib
8 shared targets
alpelisib
8 shared targets
azd
8 shared targets
torin
9 shared targets
torin1
7 shared targets
ly
9 shared targets
omipalisib
7 shared targets
idelalisib
6 shared targets
Loading evidence profile...

This evidence profile for Wortmannin is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.