Complement cascade
REACTOME PATHWAYThe Complement cascade pathway (Reactome ID: R-HSA-166658) involves 3 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Complement cascade
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Oxaprozin | — | 181 |
| 2 | Sulindac | — | 297 |
| 3 | Urea | — | 297 |
| 4 | Ursolic Acid | — | 300 |
| 5 | Bortezomib | — | 300 |
| 6 | Aurintricarboxylic Acid | — | 184 |
About the Complement cascade Pathway
The Complement cascade pathway is catalogued in Reactome (ID: R-HSA-166658) and involves 3 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include C5, C9, ELANE.