Trafficking and processing of endosomal TLR
REACTOME PATHWAYThe Trafficking and processing of endosomal TLR pathway (Reactome ID: R-HSA-1679131) involves 4 genes and is affected by 13 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Trafficking and processing of endosomal TLR
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Budesonide | — | 1,000 |
| 2 | Dibucaine | — | 299 |
| 3 | Dimethylphenylpiperazinium Iodide | — | 33 |
| 4 | Edaravone | — | 298 |
| 5 | Fluocinolone Acetonide | — | 295 |
| 6 | Podophyllotoxin | — | 14 |
| 7 | Sulfadimethoxine | — | 300 |
| 8 | vinblastine sulfate | — | 81 |
| 9 | 2-Chloroadenosine 2-Chloroadenosine. | — | 300 |
| 10 | Adenosine Diphosphate Adenosine 5'-(trihydrogen diphosphate). | — | 300 |
| 11 | Adenosine Triphosphate | — | 300 |
| 12 | Oxyphenbutazone | — | 300 |
| 13 | Triamcinolone | — | 300 |
About the Trafficking and processing of endosomal TLR Pathway
The Trafficking and processing of endosomal TLR pathway is catalogued in Reactome (ID: R-HSA-1679131) and involves 4 genes. In the BiohacksAI corpus, 13 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CTSL, HSP90B1, TLR3, TLR9.